企业邮箱
Chinese Scientist Reveals the mystery of life
2002年-09月-16日
来源：MEBO
——Successfully Regenerated 55 Types of Human or Mammalian Tissues and Organs in Situ or in Vitro
At a press release held on 8/16 ---"MEBO Science and Technology day", Prof. Xu, Rong-xiang the president of China National Burns Association (West-East), announced that they have successfully regenerated 55 types of human or mammalian tissues/organs in situ or in vitro, which reveals the mystery of life---"Potential Regenerative Cell" and special life substance.
"The human body life relies on the continuous proliferation of potential regenerative cells(2). They take place of the apoptosis or destroyed tissues and cells to make sure the normal structure and function of tissue/organ. The potential regenerative cells in human body came from the primitive multi-potential stem cells in all development and formation periods of tissue/organs. These cells involve in the formation of tissue/organs as normal cells. When the tissue/organ is destroyed, degraded or came into apoptosis, these potential regenerative cells are initialed to regenerate new cells in order to make sure the full function of tissue/organs. If this function of all the organs in human body normally bring into full play, the whole balance of human body will be maintenanced so that the healthiness and longevity will come true. On the contrary, disease will happen if this function is abnormal or part-abnormal in one organ. This is the mystery of human body life." Above is the explosive news released by Prof. Xu in press release of "MEBO Science and Technology day".
In today's conference, Prof. Xu announced the process of the discovery of life. He showed a lot of achievements in the regeneration of tissue/organs in situ or in vitro. "Why our life can last?" "Why the organs in human body can revolve without changing any parts in our whole life?" He expounded all these questions with the truly, clear and reliable results of organ regeneration and replication.
He said: "In the process of human development, primitive multi-potential stem cells not only differentiated into different functional cells, but also produced some other cells which have the potential ability of regeneration but normally stop proliferating." He called these cells as "Potential Regenerative Cells". "These cells involved in the formation of tissues/organs as normal cells, and they exist in tissue/organ as normal cells regularly. After the formation of whole body is done, the structural and functional cells continuously come into apoptosis in the process of human body metabolism. At this time, the potential regenerative cells will be initiated to regenerate, colony, and then the same cell will take place of the vacancy to make sure the balance of organs and life. It's like the well-known red cells' proliferation. The normal intestinal mucosa and epidermis tissue also repeated this process. It's nothing but that people only know these phenomena as their own, not connect these to whole life.
To discovery the mystery of life, Prof. Xu first dynamically studied the cyto-histology in the skin regeneration in situ. He found the law of skin regeneration and the regulatory life substance for regeneration, and later the map of this process was done and released in June of 2001. Then, he focused his study on the smallest unit of life---cell and its neighbors and circumstance. He found that: when lesion happened, the observed cell will be initiated to start regenerative reaction. However, when the environment is not suitable to its physiological status or when some important substance is absence, the regeneration of observed cell will stop. If we can continuously manage to maintenance the physiological environment and to supply sufficient life regenerative substance, the observed cell can be activated and differentiated continuously until take full place of the vacancy of destroyed tissue. To fulfill this procedure and to verify the existence of potential regenerative cell, Prof. Xu also designed the experimental regime of tissue/organ regeneration in vitro, so that he could directly observe if the adult tissue cell was able to initiated into potential regenerative cell and if these cells could form normal tissue/organ after that similar as stem cell(3). The results showed that there were only a few cells could be initialed in to potential regenerative cell in human body normal tissue, while most of the cells couldn't. But the potential regenerative cells are similar to stem cells; they could also form functional tissue/organs. The same results have been found not only in gastrointestinal mucosa, but also in pancreas, the renal unit, marrow, nerve, thymus, hair follicle, cardiac muscle and liver tissue and the other organs (totally 55) from all three embryo layers. By means of the reliable results of dynamic-cytology, dynamic-histology and organ regeneration in situ and in vitro, Pro. Xu has verified the existence of potential regenerative cells and their function of regeneration of functional tissue/organs in situ or in vitro similar as stem cells. This discovery and invention not only makes the life scientist's dream of organ regeneration from stem cells come true, but also decoded the mystery of life by repeating the processing of organ regenerations, which makes the study of life science directly steps into the organ regeneration in situ and clinical application without need of organ transplantation.
In the academic reports of "MEBO Science and Technology day", Prof. Xu announced the processes of the regeneration of gastrointestinal mucosa, pancreas, the renal unit, marrow, nerve, thymus, hair follicle, cardiac muscle and liver tissue and the other organs in details.
The discovery of life by Prof. Xu navigated the study direction of life science and medical research. The success of organ regeneration in situ opens a new pathway of human body life science and medical research. In the 2500 years of history, life science always developed along the path against the law of life, which was the base of the mechanical modern medicine. It is because that the idea is from the opposite of life law, not from the direction in compliance of life, the modern medicine can't break away the 2500 year railway, although modern medicine contribute a lot to people's life in all these years. Now the instrument and method of the cure of diseases and keep healthy in modern medicine is only limited in "Hold scalpel in left hand---save life temporarily in price of the lost of tissue/organ; hold poison in right hand---cure disease by using substance withstanding the law of life." There are no more sagacious choices when facing patients, even the pioneer of life science-organ replication from stem cells to cure disease, it's still relying on organ transplantation, never get rid of the fetter of traditional medicine. Prof. Xu established the systemic regenerative medicine, it shows that the adequate medicine scheme according with life condition and life activity can only be set up when apply medicine thoughts in compliance with life law so that people's healthiness and longevity can come true.
"MEBO Science and Technology day" is installed by Prof. Xu-the inventor of "skin regenerative therapy and stem cell regeneration in situ" in order to release the achievements got by MEBO scientists in regenerative medicine regularly. "MEBO Science and Technology day" is August 16 in each year for memoring August 16, 1988, Prof. Xu released his "MEBT/MEBO" in international press releases. At the same time, Chinese Ministry of Public Health approved "MEBO" as a new medicine ((88) Z-01). And then USA "Newspaper Week" reported "MEBT/MEBO" in details. During these 14 years, MEBT and MEBO became the routine medicine and therapy method in burn therapy internationally; meanwhile, the pioneer of life science-regenerative medicine-organ regeneration from stem cell in situ was set up based on "MEBT/MEBO". Therefore, the mystery of life is explained and the life scientist's dream of organ regeneration came true ahead of schedule. He promised that on this day annually he and his scientists would announce one or more research result(s) or clinical application(s) in frontier of life science and provide one or more production(s) in order to cure disease radically or to assure the function of organs.
Back in 1988, Prof. Xu brought forward to the conception of "Regenerative Medicine". After 14-year's study, he and his team have already successfully finished the tissue/organ regeneration in situ or in vitro. The life scientists predicted: "It will be at least 15 years before the tissue/organs can be regenerated from embryo stem cells in vitro." Now, Prof. Xu has already made this dream come true ahead of time, even further, they had finished the organ regeneration in situ. In science and technology, MEBO people have already finished the regeneration of 55 types of tissues/organs in situ or in vitro; they will try to complete the other 151 tissues/organs in the next 5 years to reach the target of regenerating totally 206 tissues/organs in human body. At that time, MEBO will not only bring the evangel of human body life treatment, but also the healthiness and longevity for ever.
Our goal of organ regeneration is to rehabilitate the function of organ by repairing or regenerating the destroyed organ in situ, which fulfills the human body healthiness and longevity. With the well established model of organ regeneration in vitro, we are trying to find the appropriate life substances which can initiate and maintenance the potential regenerative cells to proliferate and regenerate; and then finish the organ repairing and regeneration in situ by putting these life substances back in vivo.
Key Word:
(1) ORGAN: The physiological function unit composed by several different tissues.
(2) POTENTIAL REGENERATIVE CELL (PRC): The cells which have the regenerative ability similar as stem cells but regularly exist in organ as normal tissue cells.
(3) STEM CELL: An undifferentiated cell that has the ability to divide for indefinite periods in culture and to give rise to specialized cells to further form tissues and organs and human body.
At a press release held on 8/16 ---"MEBO Science and Technology day", Prof. Xu, Rong-xiang the president of China National Burns Association (West-East), announced that they have successfully regenerated 55 types of human or mammalian tissues/organs in situ or in vitro, which reveals the mystery of life---"Potential Regenerative Cell" and special life substance.
"The human body life relies on the continuous proliferation of potential regenerative cells(2). They take place of the apoptosis or destroyed tissues and cells to make sure the normal structure and function of tissue/organ. The potential regenerative cells in human body came from the primitive multi-potential stem cells in all development and formation periods of tissue/organs. These cells involve in the formation of tissue/organs as normal cells. When the tissue/organ is destroyed, degraded or came into apoptosis, these potential regenerative cells are initialed to regenerate new cells in order to make sure the full function of tissue/organs. If this function of all the organs in human body normally bring into full play, the whole balance of human body will be maintenanced so that the healthiness and longevity will come true. On the contrary, disease will happen if this function is abnormal or part-abnormal in one organ. This is the mystery of human body life." Above is the explosive news released by Prof. Xu in press release of "MEBO Science and Technology day".
In today's conference, Prof. Xu announced the process of the discovery of life. He showed a lot of achievements in the regeneration of tissue/organs in situ or in vitro. "Why our life can last?" "Why the organs in human body can revolve without changing any parts in our whole life?" He expounded all these questions with the truly, clear and reliable results of organ regeneration and replication.
He said: "In the process of human development, primitive multi-potential stem cells not only differentiated into different functional cells, but also produced some other cells which have the potential ability of regeneration but normally stop proliferating." He called these cells as "Potential Regenerative Cells". "These cells involved in the formation of tissues/organs as normal cells, and they exist in tissue/organ as normal cells regularly. After the formation of whole body is done, the structural and functional cells continuously come into apoptosis in the process of human body metabolism. At this time, the potential regenerative cells will be initiated to regenerate, colony, and then the same cell will take place of the vacancy to make sure the balance of organs and life. It's like the well-known red cells' proliferation. The normal intestinal mucosa and epidermis tissue also repeated this process. It's nothing but that people only know these phenomena as their own, not connect these to whole life.
To discovery the mystery of life, Prof. Xu first dynamically studied the cyto-histology in the skin regeneration in situ. He found the law of skin regeneration and the regulatory life substance for regeneration, and later the map of this process was done and released in June of 2001. Then, he focused his study on the smallest unit of life---cell and its neighbors and circumstance. He found that: when lesion happened, the observed cell will be initiated to start regenerative reaction. However, when the environment is not suitable to its physiological status or when some important substance is absence, the regeneration of observed cell will stop. If we can continuously manage to maintenance the physiological environment and to supply sufficient life regenerative substance, the observed cell can be activated and differentiated continuously until take full place of the vacancy of destroyed tissue. To fulfill this procedure and to verify the existence of potential regenerative cell, Prof. Xu also designed the experimental regime of tissue/organ regeneration in vitro, so that he could directly observe if the adult tissue cell was able to initiated into potential regenerative cell and if these cells could form normal tissue/organ after that similar as stem cell(3). The results showed that there were only a few cells could be initialed in to potential regenerative cell in human body normal tissue, while most of the cells couldn't. But the potential regenerative cells are similar to stem cells; they could also form functional tissue/organs. The same results have been found not only in gastrointestinal mucosa, but also in pancreas, the renal unit, marrow, nerve, thymus, hair follicle, cardiac muscle and liver tissue and the other organs (totally 55) from all three embryo layers. By means of the reliable results of dynamic-cytology, dynamic-histology and organ regeneration in situ and in vitro, Pro. Xu has verified the existence of potential regenerative cells and their function of regeneration of functional tissue/organs in situ or in vitro similar as stem cells. This discovery and invention not only makes the life scientist's dream of organ regeneration from stem cells come true, but also decoded the mystery of life by repeating the processing of organ regenerations, which makes the study of life science directly steps into the organ regeneration in situ and clinical application without need of organ transplantation.
In the academic reports of "MEBO Science and Technology day", Prof. Xu announced the processes of the regeneration of gastrointestinal mucosa, pancreas, the renal unit, marrow, nerve, thymus, hair follicle, cardiac muscle and liver tissue and the other organs in details.
The discovery of life by Prof. Xu navigated the study direction of life science and medical research. The success of organ regeneration in situ opens a new pathway of human body life science and medical research. In the 2500 years of history, life science always developed along the path against the law of life, which was the base of the mechanical modern medicine. It is because that the idea is from the opposite of life law, not from the direction in compliance of life, the modern medicine can't break away the 2500 year railway, although modern medicine contribute a lot to people's life in all these years. Now the instrument and method of the cure of diseases and keep healthy in modern medicine is only limited in "Hold scalpel in left hand---save life temporarily in price of the lost of tissue/organ; hold poison in right hand---cure disease by using substance withstanding the law of life." There are no more sagacious choices when facing patients, even the pioneer of life science-organ replication from stem cells to cure disease, it's still relying on organ transplantation, never get rid of the fetter of traditional medicine. Prof. Xu established the systemic regenerative medicine, it shows that the adequate medicine scheme according with life condition and life activity can only be set up when apply medicine thoughts in compliance with life law so that people's healthiness and longevity can come true.
"MEBO Science and Technology day" is installed by Prof. Xu-the inventor of "skin regenerative therapy and stem cell regeneration in situ" in order to release the achievements got by MEBO scientists in regenerative medicine regularly. "MEBO Science and Technology day" is August 16 in each year for memoring August 16, 1988, Prof. Xu released his "MEBT/MEBO" in international press releases. At the same time, Chinese Ministry of Public Health approved "MEBO" as a new medicine ((88) Z-01). And then USA "Newspaper Week" reported "MEBT/MEBO" in details. During these 14 years, MEBT and MEBO became the routine medicine and therapy method in burn therapy internationally; meanwhile, the pioneer of life science-regenerative medicine-organ regeneration from stem cell in situ was set up based on "MEBT/MEBO". Therefore, the mystery of life is explained and the life scientist's dream of organ regeneration came true ahead of schedule. He promised that on this day annually he and his scientists would announce one or more research result(s) or clinical application(s) in frontier of life science and provide one or more production(s) in order to cure disease radically or to assure the function of organs.
Back in 1988, Prof. Xu brought forward to the conception of "Regenerative Medicine". After 14-year's study, he and his team have already successfully finished the tissue/organ regeneration in situ or in vitro. The life scientists predicted: "It will be at least 15 years before the tissue/organs can be regenerated from embryo stem cells in vitro." Now, Prof. Xu has already made this dream come true ahead of time, even further, they had finished the organ regeneration in situ. In science and technology, MEBO people have already finished the regeneration of 55 types of tissues/organs in situ or in vitro; they will try to complete the other 151 tissues/organs in the next 5 years to reach the target of regenerating totally 206 tissues/organs in human body. At that time, MEBO will not only bring the evangel of human body life treatment, but also the healthiness and longevity for ever.
Our goal of organ regeneration is to rehabilitate the function of organ by repairing or regenerating the destroyed organ in situ, which fulfills the human body healthiness and longevity. With the well established model of organ regeneration in vitro, we are trying to find the appropriate life substances which can initiate and maintenance the potential regenerative cells to proliferate and regenerate; and then finish the organ repairing and regeneration in situ by putting these life substances back in vivo.
Key Word:
(1) ORGAN: The physiological function unit composed by several different tissues.
(2) POTENTIAL REGENERATIVE CELL (PRC): The cells which have the regenerative ability similar as stem cells but regularly exist in organ as normal tissue cells.
(3) STEM CELL: An undifferentiated cell that has the ability to divide for indefinite periods in culture and to give rise to specialized cells to further form tissues and organs and human body.